Fortified Procaine Penicillin for Injection

Model NO.: PI0012 Specification: OEM/GMP Trademark: AOSHUN Origin: China Mainland No animal reproduction test penicillin damage, but has not been well-controlled trials in pregnant women to eliminate the adverse effects of these drugs on the fetus, so pregnant women still need to weigh the application. Small amounts of this product from the milk secretion, breast-feeding should be suspended lactating women.

Product:	Fortified Procaine Penicillin for Injection
Ingredients	This product is sterile powder procaine penicillin and penicillin G sodium (potassium) plus Suitable suspending agents and buffers made its chemical name for aminobenzoyl 2- (diethylamino) ethyl ester ( 6R) -6- (2- phenylacetamido) - penicillanic acid monohydrate.
Formula	C13H20N2O2 ? C16H18N2O4S ? H2O
Molecular Weight	588.72
Properties	White powder.
Indications	Due to the low plasma concentration of this product, so its application is limited to penicillin highly sensitive pathogens caused mild to moderate infections such as tonsillitis caused by Group A streptococcus, scarlet fever, erysipelas, pneumococcal pneumonia, penicillin-sensitive staphylococcus GPB caused boils, carbuncles, and angina Sen Fen go far. This product can still be used to treat leptospirosis, relapsing fever and early syphilis. Dosage: This product is for intramuscular injection before use add appropriate amount of sterile water for injection into a suspension, every 400,000 to 800,000 units, 1 to 2 times.
Adverse reactions	1. allergic reaction: hives, and other rashes more common, neutropenia, interstitial nephritis, asthma attacks and serum sickness-type reactions are rare; anaphylactic shock occasionally, in the event, you must place the rescue, be maintained gas unobstructed, to measure oxygen and epinephrine, glucocorticoid therapy. 2. Herxheimer reaction and treatment contradiction: when procaine penicillin treatment of syphilis, leptospirosis and other diseases can cause symptoms intensified since the death of pathogens, called Herxheimer reaction; contradictions are seen after treatment in patients with syphilis, syphilis treatment system lesions disappeared too fast, and relatively slow tissue repair or lesion sites of fibrous tissue contraction due to impede organ function. 3. superinfection: there may be penicillin-resistant S. aureus, Gram-negative bacilli or Candida superinfection.
Contraindications	There are drugs or procaine penicillin allergy history, and procaine penicillin skin test positive or disabled patients.
NOTES	1. Before the FDA should be asked in detail about drug allergies and penicillin, procaine skin test. 2. to one penicillin allergy may be other penicillins, penicillamine allergy. 3. asthma, eczema, hay fever, urticaria and other allergic disease patients should be careful. The FDA should be freshly prepared. 5. During the application of penicillin, copper sulfate method to determine the possibility of false-positive urine, while glucose enzyme rule will not be affected; most penicillins application allows serum alanine aminotransferase or aspartate aminotransferase increased.
Pregnant and lactating women	No animal reproduction test penicillin damage, but has not been well-controlled trials in pregnant women to eliminate the adverse effects of these drugs on the fetus, so pregnant women still need to weigh the application. Small amounts of this product from the milk secretion, breast-feeding should be suspended lactating women.

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